Does any PCIe slot support NVMe SSD's automatically or do I need

Two types of M2 SSD

With standard SSDs, you can swap out your storage drive for high capacity ones up to a colossal 8TB Memory You can upgrade your RAM whenever you need to

slot machine strategies 1 x connector , integrated in the Chipset, supporting Socket 3, M key, type 22422260228022110 SSDs: Supporting PCIe

slot machine creator 2 PCIe NVMe SSD will not be compatible with your SATA port Basically, different protocols and interfaces are used in both these connections