Should I avoid _1 slot because of lane sharing with the GPU Slot

ADT-Link Key M NVMe External Graphics Card Stand Bracket with x4 Riser Cable 25cm 50cm 32Gbs for ITX STX NUC VEGA64 GTX1080ti

This design offers an additional easy to access slot for fast NVMe storage for motherboards with limited connectivity

gpu slot size Slot , 2x Thunderbolt 3 mit USB und DisplayPort , 4x USB , Gigabit m2 AMD Radeon Pro 5300 XT , 4 GByte GDDR6- RAM 27 -Glossy

gpu slot name The first PCIe x4 Slot supports the latest 25110 form factor Unlock the latch of the PCIe slot easily when remove the graphics card in the PCIe